Buy PE-22-28 for Neuroprotection & Cognitive Research with Discreet Worldwide Shipping
What is PE-22-28?
PE-22-28 is a synthetic peptide fragment derived from Diazepam Binding Inhibitor (DBI), also known as the Endozepine peptide family.
It has been studied for its neuroactive properties, showing potential to modulate GABA-A receptor activity, enhance cognitive performance, and protect neurons from stress-induced damage.
Research suggests that PE-22-28 plays a role in neuroplasticity, learning, memory formation, and anxiolytic (anti-anxiety) mechanisms — making it a key candidate for neuroscience and psychopharmacological research.
How Does PE-22-28 Work in the Body?
PE-22-28 acts as a selective modulator of the GABA-A receptor complex, binding to specific benzodiazepine sites to influence neurotransmission.
Unlike traditional benzodiazepines, PE-22-28 shows a balanced modulatory effect — potentially enhancing cognitive performance without inducing sedation.
Mechanistically, it promotes:
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Neuroprotection through reduced oxidative and excitotoxic stress
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GABAergic balance, supporting relaxation and mental focus
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Synaptic reinforcement in hippocampal regions related to learning and memory
Research has shown that PE-22-28 may also influence neuropeptide signaling involved in stress resilience and emotional regulation.
Key Research Benefits of PE-22-28
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Enhances memory retention and learning capacity in animal models
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Demonstrates neuroprotective effects against stress and toxin exposure
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Supports synaptic plasticity and cognitive resilience
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Exhibits anxiolytic properties without sedation
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Investigated for neurodegenerative disorder research (e.g., Alzheimer’s, Parkinson’s)
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May help explore novel GABA-A receptor modulation mechanisms
⚠️ PE-22-28 is for research use only. Not approved for human or therapeutic use.
Product Details and Purity
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Product Name: PE-22-28
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Category: Neuroactive Research Peptide
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Form: Lyophilized powder
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Purity: ≥99% (HPLC Tested)
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Molecular Formula: C₃₈H₆₂N₁₀O₁₀
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Molecular Weight: 838.96 g/mol
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Sequence: Ala-Gly-Phe-Thr-Ala-Arg-Ser-Ala
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Storage: Store at 2–8°C; protect from light and moisture
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Shelf Life: 24 months (unopened, stored properly)
Each batch of PE-22-28 undergoes independent third-party testing to verify purity, stability, and identity.
Dosage & Usage Guidelines
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For laboratory research use only.
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Reconstitute PE-22-28 with sterile distilled water or bacteriostatic solution under aseptic conditions.
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Use immediately after reconstitution or store aliquots at -20°C for short-term research use.
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Do not inject or ingest.
Safety, Side Effects & Precautions
PE-22-28 is not for human or animal use and must be handled in compliance with standard laboratory safety protocols.
Research data suggests minimal toxicity in preclinical trials, but human safety profiles remain untested.
Safety recommendations:
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Use gloves and eye protection during handling
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Avoid direct skin or mucosal contact
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Dispose of materials according to laboratory safety standards
Quality Assurance & Testing
At Peptide Online Store, all research peptides — including PE-22-28 — are subject to strict quality control measures, including:
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HPLC and Mass Spectrometry analysis
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Endotoxin-free certification
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Microbial sterility testing
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Batch traceability and documentation
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GMP-compliant manufacturing standards
These protocols ensure reliability and reproducibility across research environments.
Commitment to Quality and Compliance
Peptide Online Store is committed to scientific integrity, transparency, and regulatory compliance.
All peptides are manufactured under ISO 9001 and GMP guidelines, ensuring the highest level of purity and consistency for advanced research applications.
Potential Applications (For Research Use Only)
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Neuroprotection studies
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Cognitive and memory enhancement research
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Anxiety and stress modulation experiments
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Neurodegenerative disease modeling
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Synaptic signaling and plasticity analysis
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GABA receptor function and binding studies
Why Choose Peptide Online Store for PE-22-28?
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99%+ verified peptide purity
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Full COA and analytical reports provided
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Global, discreet shipping options
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Competitive pricing for bulk orders
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Trusted by neuroscience and pharmacology researchers worldwide
Shipping & Delivery Information
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Worldwide discreet shipping available
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Temperature-controlled packaging for product stability
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Orders processed within 24–48 hours
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Tracking details provided for all shipments
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Express and standard shipping options available
How to Order PE-22-28 Online
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Visit peptideonlinestore.com
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Search for PE-22-28 in the peptide catalog
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Add to cart and proceed to secure checkout
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Select preferred shipping and payment method
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Receive order confirmation and shipment tracking
Frequently Asked Questions (FAQ)
Q: What makes PE-22-28 unique compared to other neuropeptides?
A: PE-22-28 is a DBI-derived peptide fragment that specifically modulates GABA-A receptors — providing both neuroprotective and nootropic research potential.
Q: Is PE-22-28 suitable for human trials?
A: No. It is strictly for research purposes and not approved for human or therapeutic use.
Q: How stable is PE-22-28 after reconstitution?
A: It’s best used immediately after reconstitution or stored at -20°C in sterile aliquots for short-term use.
Related Research Peptides
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Selank 10mg – GABA-modulating nootropic peptide
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Semax 10mg – Neuroprotective and cognitive enhancement peptide
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DSIP (Delta Sleep-Inducing Peptide) 5mg – Sleep regulation and anti-stress peptide
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Pinealon 20mg (Bioregulator) – Brain peptide supporting mental clarity and recovery
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Cerebrolysin Peptide Complex – Neural repair and cognitive research compound
Final Thoughts
PE-22-28 is an innovative neuroactive peptide with remarkable potential in cognitive enhancement, neuroprotection, and GABA modulation research.
Its balanced mechanism and high purity make it an excellent candidate for exploring brain function, stress adaptation, and synaptic performance in controlled studies.
At Peptide Online Store, we deliver premium-grade peptides backed by verified purity, compliance, and international shipping — empowering researchers to advance their work in neuroscience and peptide-based therapeutics.
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